Shanghai Biopharmaleader co.,ltd

Date: 18th July 2016
Galeterone CAS:851983-85-2
If you are going to consult the information about 851983-85-2 from one of the leading 851983-85-2 manufacturers and suppliers in China, Biopharmaleader Co.,Ltd is always at your service.Product InformationCAS NO.851983-85-2?Product NameGaleteroneSynonymsVN/124-1; TOK 001FormulaC26H32N2OMolecular Weight388.55Spec / Purity98%minSupply CapacityDetailsGaleterone (TOK-001 or VN/124-1) is a novel steroidal antiandrogen for the treatment of prostate cancer. It possesses a unique dual mechanism of action, acting as both an androgen receptor antagonist and an inhibitor of CYP17A1, an enzyme required for the biosynthesis of the androgens. It shows selectivity for 17,20-lyase over 17-hydroxylase. As of the second half of 2014, galeterone is in phase III clinical trials for castration-resistant prostate cancer.
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