Shanghai Biopharmaleader co.,ltd

Date: 18th July 2016
Sapacitabine CAS:151823-14-2
If you are going to consult the information about 151823-14-2 from one of the leading 151823-14-2 manufacturers and suppliers in China, Biopharmaleader Co.,Ltd is always at your service.Product InformationCAS NO.151823-14-2?Product NameSapacitabineSynonymsCS-682FormulaC26H42N4O5Molecular Weight490.63Spec / Purity98%minSupply CapacityDetailsSapacitabine is a drug undergoing research for potential use in chemotherapy.Sapacitabine is an oral nucleoside analog prodrug that acts through a dual mechanism. The compound interferes with DNA synthesis by causing single-strand DNA breaks and induces arrest of the cell division cycle at G2 phase. Both sapacitabine and its major metabolite, CNDAC, have demonstrated potent anti-tumor activity in both blood and solid tumors in preclinical studies. In a liver metastatic mouse model, sapacitabine was shown to be superior to gemcitabine or 5-FU, two widely used nucleoside analogs, in delaying the onset and growth of liver metastasis.
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